马天琼 特聘研究员
Prof. Tianqiong Ma
办公室：仙林化学楼D417
邮 箱：tianqiongma@nju.edu.cn
2024-Present Assistant Professor, Nanjing University, China
2023-2024 Project Scientist, University of California, Berkeley, USA
2019-2023 Postdoc, University of California, Berkeley, USA
2018-2019 Postdoc, Peking University, China
2011-2018 Ph.D. in Organic Chemistry, Lanzhou University and Peking University, China
2010-2011 Volunteer teacher, Second Middle School of Yuzhong County, Gansu, China
2006-2010 B.S. in Material Chemistry, Lanzhou University, China
马天琼，特聘研究员，博士生导师，国家级青年人才计划（海外）入选者。2018年博士毕业于兰州大学化学化工学院（导师：王为 教授）。2018-2019年在北京大学化学与分子工程学院从事博士后研究（“博雅”博后，导师：孙俊良 教授），2019-2023年在加州大学伯克利分校从事博士后研究（导师：Omar M. Yaghi教授），2023-2024年获聘项目研究员。2024年3月加入南京大学化学化工学院。目前主要从事网络化学（Reticular Chemistry）方面的研究，包括共价有机框架、编织分子、聚索烃等材料的设计合成、晶体生长、结构解析和应用研究等。在Science、Nature. Synth.、Nature. Commun.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.等期刊上发表代表性论文。合作撰写英文专著1部，获中国授权专利3项（第二发明人）。作为主要完成人之一，获得2022年甘肃省自然科学奖特等奖。
Single-Crystal COFs.
Progress in developing new materials depends on understanding their structure. Growing large single crystals of covalent organic frameworks (COFs) represent a long-standing challenge since covalent bonding is strong so that the reversibility of reactions used to synthesize COFs are not enough to carry out self-healing, and it is difficult to avoid supersaturations sufficient to initiate spontaneous nucleation when a crystal grows by chemical reaction. We reported a general approach involving the use of aniline as a modulator to grow high-quality large single crystals of COFs held together by strong imine bonds (~600 kJ/mol). Aniline has a reactivity similar to that of COF constituents, but it is monofunctional and acts as an inhibitor to nucleation, and thus alters the crystallization process. The exceptional quality of the crystallographic data collected on these crystals enabled the anisotropic refinement of a series of COFs. These data allowed us to answer outstanding questions pertaining to reported COFs and also solve and refine with atomic precision the crystal structures of completely new ones as shown in the Figure.
Rational design and precise control of multi-dimensional complex structures.
Diverse structures result in diverse functions. Compared to inorganic molecular sieves which have hundreds of structures and pore types, and Metal-Organic Frameworks (MOFs) with more than 2,000 topologies, the limited types of skeleton and pore structures will greatly restrict the development of COFs in terms of application. If one can use simple building blocks to construct structural primitives with multiple connection modes and realize their periodic connections in three-dimensional space in one step, it will greatly enrich the structural diversity of COFs and expand more applications of COFs materials. Our strategies include: 1) Design of multifunctional small molecules to construct high-valency bond linked COFs by in situ forming cubic nodes. 2) A new structural element that constructs mechanical bonds was introduced into the frameworks to form polycatenane crystals, which related to the study of smart materials. 3) The discovery of isomers through the precisely control of synthesis conditions, bringing in different properties for the isomers with the same component.
[1] T. Ma, E. A. Kapustin, S. X. Yin, L. Liang, Z. Zhou, J. Niu, L.-H. Li., Y. Wang, J. Su, J. Li, X. Wang, W. D. Wang, W. Wang*, J. Sun*, O. M. Yaghi*, Single-crystal X-ray diffraction structures of covalent organic frameworks. Science, 2018, 361, 48. (Highlighted by Science and C&EN)
[2] T. Ma, Y. Zhou, C. S. Diercks, J. Kwon, F. Gándara, H. Lyu, N. Hanikel, P. Pena-Sánchez, Y. Liu, N. J. Diercks, R. O. Ritchie, D. M. Proserpio, O. Terasaki, O. M. Yaghi*, Catenanated covalent organic frameworks constructed from polyhedra. Nat. Synth. 2023, 2, 286. (Highlighted by C&EN et.al)
[3] C. Gropp, T. Ma, N. Hanikel, O. M. Yaghi*, Design of higher valency in covalent organic frameworks. Science, 2020, 370, eabd6406.
[4] T. Ma, L. Wei, L. Liang, S. Yin, L. Xu, J. Niu, H. Xue, X. Wang, J. Sun*, Y.-B. Zhang*, W. Wang*, Diverse crystal size effects in covalent organic frameworks. Nat. Commun. 2020, 11, 6128.
[5] T. Ma, J. Li, J. Niu, L. Zhang, A. Etman, C. Lin, D. Shi, P. Chen, L.-H. Li, X. Du, J. Sun*, W. Wang*, Observation of interpenetration isomerism in covalent organic frameworks. J. Am. Chem. Soc. 2018, 140, 6763.
[6] L. Liang, Y. Qiu, W. D. Wang, J. Han, Y. Luo, W. Yu, G.-L. Yin, Z.-P. Wang, L. Zhang, J. Ni, J. Niu, J. Sun*, T. Ma*, Wei Wang*, Non-interpenetrated single-crystal covalent organic frameworks. Angew. Chem. In. Ed. 2020, 132, 18147. (hot paper)
